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Off-site Cytotoxic Links, User Submitted

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Thu Apr 23

• Effect of yerba mate (Ilex paraguariensis ) tea on topoisomerase inhibition and oral carcinoma cell proliferation. - J Agric Food Chem. 2005 Mar 23: Effect of yerba mate (Ilex paraguariensis ) tea on topoisomerase inhibition and oral carcinoma cell proliferation. Gonzalez de Mejia E, Song YS, Ramirez-Mares MV, Kobayashi H. J Agric Food Chem. 2005 Mar 23

Thu Apr 16

• Cytotoxic T cell - Wikipedia, the free encyclopedia: A cytotoxic T cell (also known as TC, CTL, T-Killer cell, cytolytic T cell, CD8 T-cells or killer T cell) belongs to a sub-group of T lymphocytes (a type of white blood cell) that are capable of inducing the death of infected somatic or tumor cells
• In Vitro - Highly cytotoxic and neurotoxic acetogenins of the Annonaceae - Hocquemiller - Université Paris-Sud 11, Châtenay-Malab ry France FR - 2008: Acetogenins of the Annonaceae are strong inhibitors of mitochondrial complex I but discrepancies in the structure/acti vity relationships pled the search for other targets within the whole cell proteome. Combining hemisynthetic work, Cu-catalyzed Huisgen cycloaddition and proteomic techniques we have identified new putative protein targets of squamocin ruling out the previously accepted 'complex I dogma'. These results give new insights into the mechanism of action of these potent neurotoxic molecules.
• In Vitro - Squamocin, a new cytotoxic bis-tetrahydro furan containing acetogenin from Annona squamosa - Chem Pharm Bull (Tokyo) - 1988

Wed Apr 8

• In Vitro - Squamocin - a new cytotoxic bis-tetrahydro furan containing acetogenin from Annona squamosa - Fujimoto Tokyo Japan JP - 1988: Title: Squamocin, a new cytotoxic bis-tetrahydro furan containing acetogenin from Annona squamosa. Author: Fujimoto, Y : Eguchi, T : Kakinuma, K : Ikekawa, N : Sahai, M : Gupta, Y K Citation: Chem-Pharm-Bul l-(Tokyo). 1988 Dec; 36(12): 4802-6 Abstract: None Review References: None Notes: None Language: English Publication Type: Journal-Articl e Keywords: Antineoplastic Agents, Phytogenic isolation and purification : Furans isolation and purification : Lactones isolation and purification : Plants, Medicinal analysis URL: No URL associated with this record.

Mon Apr 6

• Patent - Cytotoxic annonaceous acetogenins - US7223792 - Filed - Dec 07, 2001: Acetogenins isolated from Annona muricata of the family Annonaceae are described. The substantially pure compounds of the invention exhibit to human tumor cell lines as well as selective cytotoxicity for various human tumor cell lines.

Mon Mar 9

• Patent - US7223792 - Cytotoxic annonaceous acetogenins from annona muricata - Holder - Prof Yang-Chang Wu - Kaoshiung Medical University, Taipei, Taiwan, TW - 2001-2007: Acetogenins isolated from Annona muricata of the family Annonaceae are described. The substantially pure compounds of the invention exhibit to human tumor cell lines as well as selective cytotoxicity for various human tumor cell lines. Prof Yang-Chang Wu, Editorial Board, Kaoshiung Medical University, Taipei, Taiwan, Email: yachwu@kmu.edu .tw

Tue Mar 3

• Chemotherapy - Wikipedia, the free encyclopedia

Sat Feb 14

• Snake venom types and first aid treatment

Sun Feb 8

• Docetaxel - Wikipedia, the free encyclopedia: The main use of docetaxel is the treatment of a variety of cancers after the failure of anthracycline- based chemotherapy.[ 3] Marketing of docetaxel as Taxotere is mainly towards the treatment of breast, prostate and other non-small cell cancers.[4] Clinical data has shown docetaxel to have cytotoxic activity against breast, colorectal, lung, ovarian, prostate, liver, renal, gastric, head and neck cancers, and melanoma.

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