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Fri Nov 14

• Cytotoxic substances from plants: Cytotoxic substances are toxic to cells and cause their death. Such compounds are widespread among plants. More importantly, these effects can be used for medical purposes such as suppressing growth of various tumor cells. This chapter provides an overview of the many cytotoxins and the many fungi and plants in which they naturally occur.

Fri Nov 7

• In Vivo - Antimalaria and Cytotoxic Properties of Annona Senegalensis Extract, Annonaceae - University of Ibadan, Nigeria - 2006: The in vivo animal antimalarial and in vitro cytotoxic activities of the methanol extract of Annona senegalensis Pers. (Annonaceae) was investigated in this study. The in vivo antimalarial activity of the methanol extract against Plasmodium berghei was assessed using the 4-day suppressive test procedure. The extract of A. senegalensis had intrinsic antimalarial property that were dose ? dependent. At doses of 100mg/kg weight of mice, it produced significant chemosuppressi on of parasitemia (> 57%) when administered orally. It had the highest activity at 800mg/kg weight of mice (91.1%) compared to Chloroquine disphosphate, the standard reference drug which had a chemosuppressi on of 96.2%.
• In Vitro - Actogenins, anthelmintic, antimalarial, antimicrobial, antiprotozoal, and cytotoxic antitumor - University of Tartu, Estonia: The tropical plant family Annonaceae consists of 130 genera and 2300 different species.[1] However, despite of its relatively large size, the plant family is chemically one of the least explored. The discovery of uvaricin (Fig. 1) in 1982, the first of the acetogenins, as an in vivo active antileukemic (P-388) agent, invigorated wide interest in this family.[2]

Mon Oct 6

• Most Beta-Cells Die via Inflammatory Cytokines, Not Cytotoxic T-lymphocytes | Full Text (PDF)
• Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes -- Seewaldt et al. 49 (11): 1801 -- Diabetes: Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes

Sun Apr 6

• The Australasian Society of Clinical Immunology and Allergy - Unorthodox Techniques for the Diagnosis and Treatment of Allergy, Asthma and Immune Disorders: Allergy is a science-based specialty Modern allergy practice relies on understanding the biological mechanisms underlying allergic disorders (such as asthma, hay fever or food and insect sting allergy). Accurate diagnosis is underpinned by standardized a

Thu Jan 17

• Neurosurgical FOCUS - 22(5):1 - Abstract

Tue Jan 15

• Graviola tree - Gravizon Amazon Herb Company: Graviola - A medium size shrub growing in the Amazon. Has delicious fruit called pawpaw, which is widely consumed by indigenous people. The leaf of the graviola tree contains compounds with cytotoxic activity and prevents abnormal cellular division.

Tue Jun 5

• Hyperthermia Plus Chemotherapy Nearly Doubles Disease-Free Survival Compared to Chemotherapy Alone for Sarcoma Cancer Patients: BSD Medical Corp. (Amex: BSM ) announced today that the results of a 340 patient randomized Phase III clinical trial testing the benefit of adding hyperthermia therapy to chemotherapy were presented at the annual American Society of Clinical Oncology (ASC

Tue Apr 10

• Chemotherapy - Wikipedia, the free encyclopedia: Chemotherapy is the use of chemical substances to treat disease. In its modern-day use, it refers primarily to cytotoxic drugs used to treat cancer. In its non-oncologica l use, the term may also refer to antibiotics (antibacterial chemotherapy). In tha

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